Screening Libraries
Cayman Chemical offers a unique set of compound libraries, rich in biologically active molecules, useful for screening and hit-seeking for diverse therapeutic targets.
Bio-active Lipid II Screening Library (96-Well)
237 active wells This screening library consists of 3 plates and contains 240 compounds that include prostaglandins, isoprostanes, thromboxanes, leukotrienes, lipoxins and several other complex polyunsaturated fatty acids. This collection is deal for prostanoid or other G protein-coupled receptor screening, target validation, secondary screening, validating new assays and for routine pharmacological applications. The library is provided in a 96-well format as 0.1 mM solution in DMSO.
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Bio-active Lipid I Screening Library (96-Well)
847 active wells This screening library consists of 11 plates and contains 928 compounds that include prostaglandins, thromboxanes , cannabinoids, D-myo-inositol-phosphates, phosphatidylinositol-phosphates, sphingolipids, inhibitors, receptor agonists and antagonists, ceramide derivatives, and several other complex polyunsaturated fatty acids. This collection is ideal for prostanoid or other G protein-coupled receptor screening, target validation, secondary screening, validating new assays and for routine pharmacological applications. The library is provided in a 96-well format as 1.0 mM solution in DMSO.
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Fatty Acid Screening Library (96-Well)
84 active wells This screening plate contains a variety of fatty acids with diverse biological activities as 2 mM solutions in DMSO. It includes 84 of the most commonly-ordered fatty acids, including arachidonic, linoleic, eicosapentaenoic, stearic, α- and γ-linolenic, oleic, and palmitic acids. Also includes some unusual fatty acids, including 9-thiastearic acid, 2-hydroxymyristic acid, AUDA, and CUDA.
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Kinase Screening Library (96-Well)
64 active wells This screening plate contains a variety of specific and non-specific kinase inhibitors as a 10 mM solution in DMSO. It includes 64 compounds including PD 0325901 (dual specific threonine/tyrosine kinase inhibitor), U-0126 (selective MAP kinase inhibitor), SB 203580 (p38 MAPK inhibitor), and LY294002 (PI3K inhibitor).
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Prostaglandin Screening Library I (96-Well)
87 active wells This screening plate contains a wide range of prostaglandins in the “F-series” configuration (9,11-hydroxy prostaglandins) as 2 mM solutions in DMSO. It includes 86 compounds including isoprostanes, 8-iso, dinor, and tetranor derivatives, and latanoprost, travoprost, and bimatoprost analogs.
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Prostaglandin Screening Library II (96-Well)
70 active wells This screening plate contains wide range prostaglandins in the “D and E-series” configuration (9-keto, 11-keto, 9-hydroxy, and 11-hydroxy prostaglandins) as 2 mM solutions in DMSO. It includes 70 compounds including prostaglandin metabolites, ethanolamides, and other potent analogs of prostaglandin D2 and prostaglandin E2.
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Prostaglandin Screening Library III (96-Well)
80 active wells This screening plate contains wide range prostaglandins in the “A and J-series” as 2 mM solutions in DMSO. It includes 70 compounds including thromboxanes, lactones,stable PGH and prostacylin mimics, metabolites and potent analogs of prostaglandin A2 and prostaglandin J2.
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