72510  CAY10406



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• See more Apoptosis

For active pharmaceutical ingredients (APIs) related to CAY10406, see Cayman Pharma

CAY10406 is a trifluoromethyl analog of an isatin sulfonamide compound that selectively inhibits caspases 3 and 7.1 The non-trifluoromethyl compound exhibits Ki values of 1.2 nM and 6 nM for caspases 3 and 7, respectively. For all of the other caspases tested, it is 100 to 1,000 times less potent. Caspases 3 and 7 are 'effector caspases' that are downstream from the initiating steps of apoptosis, and are implicated in the main proteolytic processing of the apoptotic signal. No data is currently available for caspase inhibition by CAY10406.
1  Lee, D., Long, S.A., Murray, J.H., et al. Potent and selective nonpeptide inhibitors of caspases 3 and 7. J Med Chem 44 2015-2026 (2001).

Download Product Insert 114 Kb PDF
Download Material Safety Data Sheet (MSDS) 118 Kb PDF

Pricing Information

Prices listed here are the Manufacturer's Suggested European Retail Price. The actual prices quoted by each individual distributor may vary. Please visit the Global Buyer's Guide on the Cayman Chemical (world) website to locate a distributor in your region.

This product is also available to buy in bulk quantities. Please contact us for a quote or to purchase.

Cayman strives to be a reliable biochemical reagent vendor by providing the best possible products and services. To ask for assistance with one of our products please contact our Technical Help staff.

Warning This product is not for human or veterinary use.

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Size Price Quantity
1 mg €26.00
5 mg €114.00
10 mg €202.00
100 mg €1,512.00
Pricing updated 2010-09-07.
Prices are subject to change without notice.