60880  eNOS (bovine recombinant)

ecNOS; NOS III; Endothelial Nitric Oxide Synthase

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• See more Enzymes; Proteins; Recombinant Proteins; Atherosclerosis; Nitric Oxide

For active pharmaceutical ingredients (APIs) related to eNOS (bovine recombinant), see Cayman Pharma

Mr: 135.00 · EC: 1.14.13.39 · Recombinant enzyme isolated from a Baculovirus overexpression system in Sf9 cells · One unit of enzyme produces 1 nmol of NO per minute at 37°C in 50 mM HEPES, pH 7.4, containing 50 µM arginine, 1 mM CaCl2, 5 µM oxyhemoglobin, 20 µg/ml calmodulin, 0.1 mM NADPH, 12 µM tetrahydrobiopterin, and 170 µM DTT.1,2,3,4
1  Hevel, J.M., Marletta, M.A. Nitric-oxide synthase assays. Methods Enzymol 233 250-258 (1994).
2  Busconi, L., Michel, T. Recombinant endothelial nitric oxide synthase: Post-translational modifications in a baculovirus expression system. Mol Pharmacol 47 655-659 (1995).
3  Sase, K., Michel, T. Expression and regulation of endothelial nitric oxide synthase. Trends Cardiovasc Med 7 28-37 (1997).
4  Verhaar, M.C., Wever, R.M.F., Kastelein, J.J.P., et al. 5-Methyltetrahydrofolate, the active form of folic acid, restores endothelial function in familial hypercholesterolemia. Circulation 97 237-241 (1998).

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Pricing Information

Prices listed here are the Manufacturer's Suggested European Retail Price. The actual prices quoted by each individual distributor may vary. Please visit the Global Buyer's Guide on the Cayman Chemical (world) website to locate a distributor in your region.

This product is also available to buy in bulk quantities. Please contact us for a quote or to purchase.

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Warning This product is not for human or veterinary use.

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10 units €147.00
Pricing updated 2010-08-01.
Prices are subject to change without notice.