600007  Prostaglandin D Synthase (hematopoietic-type) FP-Based Inhibitor Screening Assay Kit - Green

H-PGDS FP-Based Inhibitor Screening Assay Kit - Green; Prostaglandin D Synthase (hematopoietic-type) Fluorescence Polarization-Based Inhibitor Screening Assay Kit - Green




For active pharmaceutical ingredients (APIs) related to Prostaglandin D Synthase (hematopoietic-type) FP-Based Inhibitor Screening Assay Kit - Green, see Cayman Pharma

Related Articles

Kanaoka, Y., Ago, H., Inagaki, E., et al. Cloning and crystal structure of hematopoietic prostaglandin D synthase. Cell 90 1085-1095 (1997).

Zhang, J., Chung, T.D.Y., Oldenburg, K.R. A simple statistical parameter for use in evaluation and validation of high throughput screening assays. J Biomol Screen 4(2) 67-73 (1999).

Pinzar, E., Miyano, M., Kanaoka, Y., et al. Structural basis of hematopoietic prostaglandin D synthase activity elucidated by site-directed mutagenesis. J Biol Chem 275(40) 31239-31244 (2000).

Inoue, T., Okano, Y., Kado, Y., et al. First determination of the inhibitor complex structure of human hematopoietic prostaglandin D synthase. J Biochem 135 279-283 (2004).

Aritake, K., Kado, Y., Inoue, T., et al. Structural and functional characterization of HQL-79, an orally selective inhibitor of human hematopoietic prostaglandin D synthase. J Biol Chem 281(22) 15277-15286 (2006).

Matsushita, K., Nobutoshi, A., Hizue, A. Pharmacological studies on the novel antiallergic drug HQL-79: I. Antiallergic and antiasthmatic effects in various experimental models. Jpn J Pharmacol 78(1) 1-10 (1998).

Matsushita, K., Nobutoshi, A., Aritake, K. Pharmacological studies on the novel antiallergic drug HQL-79: II. Elucidation of mechanisms for antiallergic and antiasthmatic effects. Jpn J Pharmacol 78(1) 11-22 (1998).

Hohwy, M., Spadola, L., Lundquist, B., et al. Novel prostaglandin D synthase inhibitors generated by fragment-based drug design. J Med Chem 51 2178-2186 (2008).


Download Kit Booklet 1136 Kb PDF
Download Material Safety Data Sheet (MSDS) 63 Kb PDF

Pricing Information

Prices listed here are the Manufacturer's Suggested European Retail Price. The actual prices quoted by each individual distributor may vary. Please visit the Global Buyer's Guide on the Cayman Chemical (world) website to locate a distributor in your region.

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Warning This product is not for human or veterinary use.

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384 wells €420.00
1,920 wells €1,576.00
Pricing updated 2010-08-01.
Prices are subject to change without notice.