589324  DNA Methylation EIA Kit

5-methyl-2-deoxy Cytidine ELISA Kit



• See below for pricing and ordering
• See more EIA (Enzyme Immunoassay); Assay Kits; Cancer; DNA Damage and Repair; Epigenetics

You may be eligible to receive a free sample DNA Methylation EIA Kit under the Cayman Challenge program.

Cayman offers free EIA analysis tools you may find helpful.

Let Cayman analyze your samples for you. See EIA Service for details and availability.

For active pharmaceutical ingredients (APIs) related to DNA Methylation EIA Kit, see Cayman Pharma

Related Articles

Clark, S.J., Melki, J. DNA methylation and gene silencing in cancer: Which is the guilty party?. Oncogene 21 5380-5387 (2002).

Robertson, K.D. DNA, methylation and chromatin-unraveling the tangled web. Oncogene 21 5361-5379 (2002).

Itoh, K., Aida, S., Ishiwata, S., et al. Immunochemical detection of urinary 5-methyl-2'-deoxycytidine as a potential biologic marker for leukemia. Clin Chim Acta 234 37-45 (1995).

Mizugaki, M., Itoh, K., Yamaguchi, T., et al. Preparation of a monoclonal antibody specific for 5-methyl-2'-deoxycytidine and its application for the detection of DNA methylation levels in human peripheral blood cells. Biol Pharm Bull 12 1537-1540 (1996).

Reynaud, C., Bruno, C., Boullanger, P., et al. Monitoring of urinary excretion of modified nucleosides in cancer patients using a set of six monoclonal antibodies. Cancer Lett (1991).

Linhart, H.G., Lin, H., Yamada, Y. DNMT3b promotes tumorigenesis in vivo by gene-specific de novo methylation and transcriptional silencing. Genes Dev 21 3110-3122 (2007).

Ushijima, T. Detection and interpretation of altered methylation patterns in cancer cells. Cancer 5 223-231 (2005).

Greger, V., Passarge, E., Höpping, W., et al. Epigenetic changes may contribute to the formation and spontaneous regression of retinoblastoma. Hum Genet 83 155-158 (1989).

Pradelles, P., Grassi, J., Maclouf, J.A. Enzyme immunoassays of eicosanoids using acetylcholinesterase as label: An alternative to radioimmunoassay. Anal Chem 57 1170-1173 (1985).

Maxey, K.M., Maddipati, K.R., Birkmeier, J. Interference in enzyme immunoassays. J Clin Immunoassay 15 116-120 (1992).

Ahuja, N., Li, Q., Mohan, A.L., et al. Aging and DNA methylation in colorectal mucosa and cancer. Cancer Res 58 5489-5494 (1998).

Issa, J.J., Ottaviano, Y.L., Celano, P., et al. Methylation of the oestrogen receptor CpG island links ageing and neoplasia in human colon. Nat Genet 7 536-540 (1994).

Waki, T., Tamura, G., Sato, M., et al. Age-related methylation of tumor suppressor and tumor-related genes: An analysis of autopsy samples. Oncogene 22 4128-4133 (2003).

Wilson, V.L., Smith, R.A., Autrup, H., et al. Genomic 5-methylcytosine determination by 32P-postlabeling analysis. Anal Biochem 152 275-284 (1986).

Flotho, C., Claus, R., Batz, C., et al. The DNA methyltransferase inhibitors azacitidine, decitabine and zebularine exert differential effects on cancer gene expression in acute myeloid leukemia cells. Leukemia (2009).

Maclouf, J., Grassi, J., Pradelles, P. Development of enzyme-immunoassay techniques for the measurement of eicosanoids. (1987).


Download Kit Booklet 713 Kb PDF
Download Abbreviated Kit Protocol 425 Kb PDF

Pricing Information

Prices listed here are the Manufacturer's Suggested European Retail Price. The actual prices quoted by each individual distributor may vary. Please visit the Global Buyer's Guide on the Cayman Chemical (world) website to locate a distributor in your region.

This product is also available to buy in bulk quantities. Please contact us for a quote or to purchase.

Cayman strives to be a reliable biochemical reagent vendor by providing the best possible products and services. To ask for assistance with one of our products please contact our Technical Help staff.

Warning This product is not for human or veterinary use.

Item total €0.00
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Size Price Quantity
96 wells €462.00
480 wells €1,733.00
Pricing updated 2010-08-01.
Prices are subject to change without notice.

Many of our kits require a source of UltraPure Water. If you do not have a source it is available for purchase from Cayman Chemical. Please check the Additional Items Required section of this kit booklet to verify if Ultra Pure Water is needed. Please note that the 480 well kits are supplied with a single 500 dtn vial of tracer and antiserum that must be used within the stated time following reconstitution. Please see the individual kit booklets for these details or contact techserv@caymanchem.com.