589320  DNA/RNA Oxidative Damage EIA Kit

8-OH-2dG; 8-OH-DG; 8-hydroxy-2'-Deoxyguanosine; DNA/RNA Oxidative Damage ELISA




You may be eligible to receive a free sample DNA/RNA Oxidative Damage EIA Kit under the Cayman Challenge program.

Cayman offers free EIA analysis tools you may find helpful.

Let Cayman analyze your samples for you. See EIA Service for details and availability.

For active pharmaceutical ingredients (APIs) related to DNA/RNA Oxidative Damage EIA Kit, see Cayman Pharma

Limit of detection: 80% B/B0: ~30 pg/ml · Sensitivity: 50% B/B0: ~100 pg/ml · Both DNA and RNA are damaged by oxidation during aging and in a variety disease states including cancer. The repair processes that are initiated to correct this damage release multiple oxidized guanine species into the urine. Cayman Chemical has developed this immunoassay for the measurement of DNA/RNA oxidative damage that detects all three oxidized guanine species; 8-hydroxy-2'-deoxyguanosine from DNA, 8-hydroxyguanosine from RNA, and 8-hydroxyguanine from either DNA or RNA. Some commercial vendors offer immunoassays that detect only 8-hydroxy-2'-deoxyguanosine, and not the other two molecules. The advantage of the Cayman kit is that it captures a more complete set of biologically relevant products of oxidative damage than do assays that are restricted to analysis of only 8-hydroxy-2'-deoxyguanosine. However, because Cayman’s kit recognizes more than 8-hydroxy-2'-deoxyguanosine, it is not valid to compare the results from the Cayman EIA Kit to an LC/MS analysis of 8-hydroxy-2'-deoxyguanosine. The EIA value will always be significantly higher than LC/MS because the EIA also detects 8-hydroxyguanosine and 8-hydroxyguanine.

Download Kit Booklet 694 Kb PDF
Download Abbreviated Kit Protocol 421 Kb PDF
Download Material Safety Data Sheet (MSDS) 407 Kb PDF

Pricing Information

Prices listed here are the Manufacturer's Suggested European Retail Price. The actual prices quoted by each individual distributor may vary. Please visit the Global Buyer's Guide on the Cayman Chemical (world) website to locate a distributor in your region.

This product is also available to buy in bulk quantities. Please contact us for a quote or to purchase.

Cayman strives to be a reliable biochemical reagent vendor by providing the best possible products and services. To ask for assistance with one of our products please contact our Technical Help staff.

Warning This product is not for human or veterinary use.

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Size Price Quantity
96 strip wells €450.00
96 solid wells €450.00
480 strip wells €1,688.00
480 solid wells €1,688.00
Pricing updated 2013-05-25.
Prices are subject to change without notice.

Many of our kits require a source of UltraPure Water. If you do not have a source it is available for purchase from Cayman Chemical. Please check the Additional Items Required section of this kit booklet to verify if Ultra Pure Water is needed. Please note that the 480 well kits are supplied with a single 500 dtn vial of tracer and antiserum that must be used within the stated time following reconstitution. Please see the individual kit booklets for these details or contact techserv@caymanchem.com.