514531  Prostaglandin E Metabolite EIA Kit

Prostaglandin E Metabolite ELISA Kit; PGEM EIA Kit; PGE Metabolite EIA Kit



• See below for pricing and ordering
• See more EIA (Enzyme Immunoassay); Assay Kits; Prostaglandins

You may be eligible to receive a free sample Prostaglandin E Metabolite EIA Kit under the Cayman Challenge program.

Cayman offers free EIA analysis tools you may find helpful.

Let Cayman analyze your samples for you. See EIA Service for details and availability.

For active pharmaceutical ingredients (APIs) related to Prostaglandin E Metabolite EIA Kit, see Cayman Pharma

Limit of detection: 80% B/B0: 2 pg/ml · Sensitivity: 50% B/B0: 11 pg/ml · Prostaglandin E2 (PGE2) is produced by a variety of cell types which, in general, do not contain the enzymes required for metabolism of PGE2. Thus, cultured endothelial cells or osteoblasts will release PGE2 into the culture medium, where it will accumulate without appreciable metabolism. The direct assay of PGE2 from the medium is a good way to measure PGE2 production from these cells. PGE2 is rapidly converted in vivo to its 13,14-dihydro-15-keto metabolite, with more than 90% of circulating PGE2 cleared by a single passage through the lungs. Unfortunately, this metabolite is not chemically stable and undergoes a variable amount of degradation to PGA products. For this reason, blood, urine, or other samples from whole animals or humans often contain very little intact PGE2, and measurement of the metabolites is necessary to provide a reliable estimate of actual PGE2 production. Cayman’s PGE Metabolite assay was developed as a method of converting 13,14-dihydro-15-keto PGA2 and 13,14-dihydro-15-keto PGE2 to a single, stable derivative that could be easily quantified by EIA. This assay is therefore the method of choice if the samples in question have undergone extensive metabolism prior to collection.

Download Kit Booklet 920 Kb PDF
Download Abbreviated Kit Protocol 438 Kb PDF
Download Material Safety Data Sheet (MSDS) 264 Kb PDF

Pricing Information

Prices listed here are the Manufacturer's Suggested European Retail Price. The actual prices quoted by each individual distributor may vary. Please visit the Global Buyer's Guide on the Cayman Chemical (world) website to locate a distributor in your region.

This product is also available to buy in bulk quantities. Please contact us for a quote or to purchase.

Cayman strives to be a reliable biochemical reagent vendor by providing the best possible products and services. To ask for assistance with one of our products please contact our Technical Help staff.

Warning This product is not for human or veterinary use.

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Size Price Quantity
96 wells €320.00
480 wells €1,198.00
Pricing updated 2010-08-01.
Prices are subject to change without notice.

Many of our kits require a source of UltraPure Water. If you do not have a source it is available for purchase from Cayman Chemical. Please check the Additional Items Required section of this kit booklet to verify if Ultra Pure Water is needed. Please note that the 480 well kits are supplied with a single 500 dtn vial of tracer and antiserum that must be used within the stated time following reconstitution. Please see the individual kit booklets for these details or contact techserv@caymanchem.com.