500501  Prostaglandin E2 FPIA Kit - Green

PGE2 Fluorescence Polarization Immunoassay - Green



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• See more Fluorescence Polarization; Assay Kits; Prostaglandins; Immunology; Inflammation

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Prostaglandin E2 (PGE2) is one of the primary prostaglandins formed from the coupled metabolism of arachidonic acid by the cyclooxygenases (COX-1 and COX-2) and PGE synthases (microsomal and/or cytosolic). Its activity influences inflammation, fertility and parturition, gastric mucosal integrity, and immune modulation.1,2,3,4 Cayman Chemical’s PGE2 Fluorescence Polarization Immunoassay (FPIA) - Green is a break-through method for rapid, high-throughput screening of PGE2 samples. It is now possible to rapidly analyze samples and increase the rate of lead compound identification without the time-consuming incubation, washing, and development steps of a solid phase EIA.This FPIA is a homogenous, single-step assay which is easily adaptable to robotic assay systems. Simply mix the sample or standard with the assay cocktail, incubate at least 60 minutes, and read the plate whenever you are ready. Each kit contains FPIA reagent, buffer concentrate (10X), standard, 384 well plate, foil plate cover, and complete instructions.
1  Willis, A.L., Cornelsen, M. Repeated injection of prostaglandin E2 in rat paws induces chronic swelling and a marked decrease in pain threshold. Prostaglandins 3 353-357 (1973).
2  Jackson, G.M., Sharp, H.T., Varner, M.W. Cervical ripening before induction of labor: A randomized trial of prostaglandin E2 gel versus low-dose oxytocin. Am J Obstet Gynecol 171 1092-1096 (1994).
3  Robert, A., Schultz, J.R., Nezamis, J.E., et al. Gastric antisecretory and antiulcer properties of PGE2, 15-methyl PGE2, and 16,16-dimethyl PGE2. Intravenous, oral and intrajejunal administration. Gastroenterology 70 359-370 (1976).
4  Arvind, P., Papavassiliou, E.D., Tsioulias, G.J., et al. Prostaglandin E2 down-regulates the expression of HLA-DR antigen in human colon adenocarcinoma cell lines. Biochemistry 34 5604-5609 (1995).

Download Kit Booklet 1300 Kb PDF
Download Material Safety Data Sheet (MSDS) 38 Kb PDF

Pricing Information

Prices listed here are the Manufacturer's Suggested European Retail Price. The actual prices quoted by each individual distributor may vary. Please visit the Global Buyer's Guide on the Cayman Chemical (world) website to locate a distributor in your region.

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Warning This product is not for human or veterinary use.

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Size Price Quantity
384 wells €190.00
1920 wells €712.00
Pricing updated 2010-08-01.
Prices are subject to change without notice.