500430  Mouse Anti-Type II Collagen IgG Assay Kit (chick)




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Limit of detection: 15.6 U/ml · Collagen-induced arthritis (CIA) is an experimental autoimmune disease that is widely used as a model of human rheumatoid arthritis (RA) in the study of the pathogenic mechanisms of this disease and for testing potential therapeutics. Circulating levels of anti-type II collagen antibody are strongly associated with the development of arthritis and can be used as a biomarker of CIA. Cayman’s Mouse Anti-Type II Collagen IgG Assay is an immunometric (i.e., sandwich) assay which can be used to measure anti-type II collagen antibody in plasma or serum without prior sample purification. This kit uses a chick collagen-coated plate and an affinity-purified polyclonal antibody isolated from mice with CIA as a standard. This standard provides the most accurate measurement of anti-CII concentration in experimental plasma samples. One unit of standard in this assay is approximately equal to 1 ng of IgG protein. The standard curve spans the range of 15.6-1,000 U/ml, with a LLOQ of 15.6 U/ml.

Download Kit Booklet 557 Kb PDF
Download Material Safety Data Sheet (MSDS) 305 Kb PDF

Pricing Information

Prices listed here are the Manufacturer's Suggested European Retail Price. The actual prices quoted by each individual distributor may vary. Please visit the Global Buyer's Guide on the Cayman Chemical (world) website to locate a distributor in your region.

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Warning This product is not for human or veterinary use.

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Size Price Quantity
96 wells €390.00
Pricing updated 2014-07-31.
Prices are subject to change without notice.

Many of our kits require a source of UltraPure Water. If you do not have a source it is available for purchase from Cayman Chemical. Please check the Additional Items Required section of this kit booklet to verify if Ultra Pure Water is needed. Please note that the 480 well kits are supplied with a single 500 dtn vial of tracer and antiserum that must be used within the stated time following reconstitution. Please see the individual kit booklets for these details or contact techserv@caymanchem.com.