Luminex® LTB4 Kit
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|Limit of detection: 80% B/B0: 24 pg/ml · Sensitivity: 50% B/B0: 138 pg/ml · Leukotriene B4 (LTB4) is a potent mediator of inflammation that stimulates a number of leukocyte functions, including aggregation, stimulation of ion fluxes, enhancement of lysosomal enzyme release, superoxide anion production, chemotaxis, and chemokinesis. In subnanomolar ranges (3.9 x 10−10 M), LTB4 causes chemotaxis and chemokinesis in human PMNLs. At higher concentrations, (1.0 x 10−7 M), LTB4 leads to neutrophil aggregation and degranulation as well as superoxide anion production. Plasma levels of LTB4 increase from <100 pg/ml to >100 ng/ml following leukocyte stimulation. Cayman’s Luminex® LTB4 Kit can be used for quantification of LTB4 in plasma, culture media, and other sample matrices. This kit typically displays an IC50 (50% B/B0) of approximately 140 pg/ml and a detection limit (80% B/B0) of approximately 25 pg/ml.|
|Download Kit Booklet 646 Kb PDF|
|Download Material Safety Data Sheet (MSDS) 51 Kb PDF|
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Warning This product is not for human or veterinary use.
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Many of our kits require a source of UltraPure Water. If you do not have a source it is available for purchase from Cayman Chemical. Please check the Additional Items Required section of this kit booklet to verify if Ultra Pure Water is needed. Please note that the 480 well kits are supplied with a single 500 dtn vial of tracer and antiserum that must be used within the stated time following reconstitution. Please see the individual kit booklets for these details or contact email@example.com.