13919  IκBα Polyclonal Antibody (aa 34-48)



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• See more Western Blot; Antibodies; NF-κB; Inflammation

For active pharmaceutical ingredients (APIs) related to IκBα Polyclonal Antibody (aa 34-48), see Cayman Pharma

Antigen: synthetic peptide corresponding to human IκBα amino acids 34-48 · Host: rabbit · Application(s): WB · NF-κB is silenced in the cytoplasm by an inhibitory protein IkB.1 Synthesis of IκBα is autoregulated.2 IκB proteins are phosphorylated by IκB kinase complex consisting of at least three proteins, IKK1/α, IKK2/β, and IKK3/γ.3,4,5,6 External stimuli such as tumor necrosis factor or other cytokines induce phosphorylation and degradation of IκB releasing NF-κB dimers. NF-κB dimers subsequently translocate to the nucleus and activate target genes. Six members of the IkB family members have been identified.1 One of the first genes induced following NF-κB activation is IκBα.
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Pricing Information

Prices listed here are the Manufacturer's Suggested European Retail Price. The actual prices quoted by each individual distributor may vary. Please visit the Global Buyer's Guide on the Cayman Chemical (world) website to locate a distributor in your region.

This product is also available to buy in bulk quantities. Please contact us for a quote or to purchase.

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Warning This product is not for human or veterinary use.

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1 ea €310.00
Pricing updated 2013-05-26.
Prices are subject to change without notice.