13848  MEKK2 Polyclonal Antibody

MAPKKK2; MAP3K2; MAP Kinase Kinase Kinase 2; Dual Specificity MAP Kinase Kinase Kinase 2; MAP Kinase/ERK Kinase Kinase 2

For active pharmaceutical ingredients (APIs) related to MEKK2 Polyclonal Antibody, see Cayman Pharma

Antigen: synthetic peptide within the region of human MEKK2 amino acids 1-50 · Host: rabbit · Application(s): IHC (paraffin embedded-sections) and WB · MEKK2 is a serine/threonine protein kinase, belonging to the mitogen-activated protein kinase (MAPK) family. It plays an important role in activation of MAPK and preferentially activates other kinases involved in the MAPK signaling pathway. MEKK2 is known to directly phosphorylate and activate IκB kinases, and thus plays a role in the NF-κB signaling pathway. It regulates T-cell function, controls cytokine gene expression in mast cells, mediates epidermal growth factor receptors and fibroblast growth factor-2 receptor signals, and plays a role in rheumatoid arthritis. It is also involved in LPS-TLR4 signaling, due to its phosphorylation after TLR4 activation by LPS.

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Pricing Information

Prices listed here are the Manufacturer's Suggested European Retail Price. The actual prices quoted by each individual distributor may vary. Please visit the Global Buyer's Guide on the Cayman Chemical (world) website to locate a distributor in your region.

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Pricing updated 2014-04-19.
Prices are subject to change without notice.