13130  trans-Resveratrol-d4

(E)-Resveratrol-d4 (CAS 1089051-56-8)

trans-Resveratrol-d4 contains four deuterium atoms at the 2, 3, 5, and 6 positions. It is intended for use as an internal standard for the quantification of trans-resveratrol by GC- or LC-mass spectrometry. Phenolic compounds, particularly flavonoids, from plant sources have long been observed to have antioxidant activity with potential benefits for human health.1,2,3 trans-Resveratrol is a potent phenolic antioxidant found in grapes and red wine that also has antiproliferative and anti-inflammatory activity.4 trans-Resveratrol is also a selective inhibitor of cyclooxygenase 1 (COX-1).5 It inhibits COX and peroxidase activities of COX-1 with ED50 values of 15 and 3.7 µM, respectively, with essentially no inhibition of the COX activity of COX-2.
1  L. Frémont, L. Belguendouz and S. Delpal. Antioxidant activity of resveratrol and alcohol-free wine polyphenols related to LDL oxidation and polyunsaturated fatty acids. Life Sciences 64 2511-2521 (1999).
2  J. L. Johnson and K. R. Maddipati. Paradoxical effects of resveratrol on the two prostaglandin H synthases. Prostaglandins & Other Lipid Mediators 56 131-143 (1998).
3  S. Rotondo, G. Rajtar, S. Manarini, et al. Effect of trans-resveratrol, a natural polyphenolic compound, on human polymorphonuclear leukocyte function. British Journal of Pharmacology 123 1691-1699 (1998).
4  N. J. Miller and C. Rice-Evans. Antioxidant activity of resveratrol in red wine. Clinical Chemistry 41 1789-1789 (1995).
5  M. Jang, L. Cai, G. O. Udeani, et al. Cancer chemopreventive activity of resveratrol, a natural product derived from grapes. Science 275 218-220 (1997).

Download Product Insert 111 Kb PDF
Download Material Safety Data Sheet (MSDS) 28 Kb PDF

Pricing Information

Prices listed here are the Manufacturer's Suggested European Retail Price. The actual prices quoted by each individual distributor may vary. Please visit the Global Buyer's Guide on the Cayman Chemical (world) website to locate a distributor in your region.

This product is also available to buy in bulk quantities. Please contact us for a quote or to purchase.

Cayman strives to be a reliable biochemical reagent vendor by providing the best possible products and services. To ask for assistance with one of our products please contact our Technical Help staff.

Warning This product is not for human or veterinary use.

Item total €0.00
Shopping cart total €0.00
Size Price Quantity
100 µg €49.00
250 µg €117.00
500 µg €220.00
1 mg €390.00
Pricing updated 2017-01-19.
Prices are subject to change without notice.