10546  7(S),17(S)-dihydroxy-8(E),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic Acid

7(S),17(S)-hydroxy DPA (CAS 887752-13-8)

Novel oxylipins, referred to as docosanoids, have been derived from C22 polyunsaturated fatty acids 7(S),17(S)-dihydroxy-8(E),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic acid (7(S),17(S)-hydroxy DPA) is a DPA-derived analog of the 17(S)-dihydroxy series of docosanoids known as protectins. Protectin D1, a DHA-derived dihydroxy fatty acid, exhibits potent anti-inflammatory activities.1,2,3 Potentially, 7(S),17(S)-hydroxy DPA demonstrates similar properties; however, its biological activity has yet to be determined.
1  C. N. Serhan, K. Gotlinger, S. Hong, et al. Anti-inflammatory actions of neuroprotectin D1/protectin D1 and its natural stereoisomers: Assignments of dihydroxy-containing docosatrienes. Journal of Immunology 176 1848-1859 (2006).
2  A. Ariel and C. N. Serhan. Resolvins and protectins in the termination program of acute inflammation. TRENDS in Immunology 28(4) 176-183 (2007).
3  J. M. Schwab, N. Chiang, M. Arita, et al. Resolvin E1 and protectin D1 activate inflammation-resolution programmes. Nature 447 869-875 (2007).

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25 µg €45.00
50 µg €85.00
100 µg €163.00
Pricing updated 2017-01-19.
Prices are subject to change without notice.