10260  13,14-dihydro-15-keto Prostaglandin A2

13,14-dihydro-15-keto PGA2 (CAS 74872-89-2)




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PGE2 is metabolized rapidly to 13,14-dihydro-15-keto PGE2, which is present in the plasma of humans and other mammals. 13,14-dihydro-15-keto PGA2 results from the non-enzymatic dehydration of 13,14-dihydro-15-keto PGE2, a process which is accelerated by the presence of albumin.1,2 Further decomposition of 13,14-dihydro-15-keto PGA2 by the intentional addition of base produces bicyclo PGE2, a stable marker of PGE2 biosynthesis.2
1  Granström, E., Hamberg, M., Hansson, G., et al. Chemical instability of 15-keto-13,14-dihydro-PGE2: The reason for low assay reliability. Prostaglandins 19 933-945 (1980).
2  Fitzpatrick, F.A., Aguirre, R., Pike, J.E., et al. The stability of 13,14-dihydro-15 keto-PGE2. Prostaglandins 19 917-931 (1980).

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Pricing Information

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Size Price Quantity
1 mg €76.00
5 mg €341.00
10 mg €605.00
50 mg €2,646.00
Pricing updated 2010-09-07.
Prices are subject to change without notice.