For active pharmaceutical ingredients (APIs) related to HDAC1 Inhibitor Screening Assay Kit, see Cayman Pharma
Histone deacetylases (HDACs) catalyze the hydrolytic removal of acetyl groups from histone lysine residues resulting in chromatin condensation and transcriptional repression of chromosomal DNA. Thus, HDAC inhibition allows the conformation of DNA to be relaxed and transcriptional activation to ensue. Changes in the transcription of key genes have linked HDAC inhibitors to blocking angiogenesis and cell cycling, and promoting apoptosis and differentiation. Cayman’s HDAC1 Inhibitor Screening Assay Kit provides a fast, fluorescence-
Sold under license from Cyclex.
|Download Kit Booklet 310 Kb PDF|
|Download Material Safety Data Sheet (MSDS) 95 Kb PDF|
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Warning This product is not for human or veterinary use.
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