10010252  Methyl-L-NIO (hydrochloride)

(CAS 150403-96-6)



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Nitric oxide synthase (NOS) catalyzes the conversion of L-arginine to nitric oxide (NO) and citrulline. Methyl-L-NIO (hydrochloride) is a competitive NOS inhibitor that competes with L-arginine for the amino acid binding site. It is a more potent inhibitor of nNOS (Ki = 3.0 µM) than eNOS (Ki = 10.0 µM) or iNOS (Ki = 9.5 µM).1
1  Babu, B.R., Griffith, O.W. N5-(1-Imino-3-butenyl)-L-ornithine. A neuronal isoform selective mechanism-based inactivator of nitric oxide synthase. J Biol Chem 273 8882-8889 (1998).

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Pricing Information

Prices listed here are the Manufacturer's Suggested European Retail Price. The actual prices quoted by each individual distributor may vary. Please visit the Global Buyer's Guide on the Cayman Chemical (world) website to locate a distributor in your region.

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Size Price Quantity
5 mg €60.00
10 mg €114.00
25 mg €270.00
50 mg €480.00
Pricing updated 2010-08-01.
Prices are subject to change without notice.