10009431  1-Stearoyl-2-Arachidonoyl PC-d8

SAPC-d8; 1-Stearoyl-2-Arachidonoyl Phosphatidylcholine-d8




For active pharmaceutical ingredients (APIs) related to 1-Stearoyl-2-Arachidonoyl PC-d8, see Cayman Pharma

1-Stearoyl-2-Arachidonoyl PC-d8 contains eight deuterium atoms at the 5, 6, 8, 9, 11, 12, 14, and 15 positions. It is intended for use as an internal standard for the quantification of SAPC by GC- or LC-mass spectrometry. Oxidation of phospholipids in low-density lipoprotein (LDL) generates pro-inflammatory and pro-thrombotic mediators that may play a crucial role in cardiovascular and inflammatory diseases.1 1-stearoyl-2-arachidonoyl-sn-Glycero-3-phosphocholine (SAPC) is one of the major phospholipid species in LDL. Upon oxidation, SAPC that been shown to induce monocyte-endothelial interactions.2
1  Milne, G.L., Seal, J.R., Havrilla, C.M., et al. Identification and analysis of products formed from phospholipids in the free radical oxidation of human low density lipoproteins. J Lipid Res 46 307-319 (2005).
2  Subbanagounder, G., Leitinger, N., Schwenke, D.C., et al. Determinants of bioactivity of oxidized phospholipids: Specific oxidized fatty acyl groups at the sn-2 position. Arterioscler Thromb Vasc Biol 20 2248-2254 (2000).

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Pricing Information

Prices listed here are the Manufacturer's Suggested European Retail Price. The actual prices quoted by each individual distributor may vary. Please visit the Global Buyer's Guide on the Cayman Chemical (world) website to locate a distributor in your region.

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Size Price Quantity
50 µg €51.00
100 µg €90.00
500 µg €384.00
1 mg €660.00
Pricing updated 2010-08-01.
Prices are subject to change without notice.