10008617  Arachidonic Acid Leelamide




For active pharmaceutical ingredients (APIs) related to Arachidonic Acid Leelamide, see Cayman Pharma

Arachidonic acid leelamide is the arachidonic amide analog of leelamine. Leelamine has weak affinity for the human central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors, exhibiting 20% displacement of [3H]-CP55940 at a concentration of 10 µM.1 Leelamine inhibits pyruvate dehydrogenase kinase (PDK) with an IC50 value of 9.5 µM.2 Derivatives of leelamine exhibit anti-inflammatory activity and show moderate inhibition of phospholipase A2 activity from a variety of sources.3 There are no published studies of the pharmacological properties of arachidonic acid leelamide.
1  Martin, B.R. Leelamine. (2006 Apr 27).
2  Aicher, T.D., Damon, R.E., Koletar, J., et al. Triterpene and diterpene inhibitors of pyruvate dehydrogenase kinase (PDK). Bioorg Med Chem Lett 9 2223-2228 (1999).
3  Wilkerson, W., DeLucca, I., Galbraith, W., et al. Antiinflammatory phospholipase-A2 inhibitors. I. Eur J Med Chem 26 667-676 (1991).

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Pricing Information

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Size Price Quantity
5 mg €54.00
10 mg €104.00
50 mg €432.00
100 mg €756.00
Pricing updated 2010-08-01.
Prices are subject to change without notice.