10006488  Gestrinone

(CAS 16320-04-0)



• See below for pricing and ordering
• See more Hormone; Steroids; Endocrinology

For active pharmaceutical ingredients (APIs) related to Gestrinone, see Cayman Pharma

Endometriosis is common disease characterized by the presence of endometrial tissue outside the uterus which affects approximately 10% of premenopausal women. Gestrinone is a synthetic steroid used occasionally to treat endometriosis.1 It acts centrally on the hypothalamic-pituitary system to suppress release of lutenizing hormone (LH) and follicle-stimulating hormone (FSH), thus reducing estrogen synthesis.1 It also binds to androgen (AR), progesterone (PR), and estrogen (ER) receptors in the human endometrial tissue but not to steroid hormone binding globulin or corticord-binding globulin.2 Gestrinone binds to AR and PR with EC50 values of approximately 20 and 30 nM, respectively.3 These values reflect approximately 5-6 fold lower affinity than testosterone and progesterone, the natural AR and PR ligands, for these receptors.3
1  missing reference text
2  missing reference text
3  missing reference text

Download Product Insert 86 Kb PDF
Download Material Safety Data Sheet (MSDS) 19 Kb PDF

Pricing Information

Prices listed here are the Manufacturer's Suggested European Retail Price. The actual prices quoted by each individual distributor may vary. Please visit the Global Buyer's Guide on the Cayman Chemical (world) website to locate a distributor in your region.

This product is also available to buy in bulk quantities. Please contact us for a quote or to purchase.

Cayman strives to be a reliable biochemical reagent vendor by providing the best possible products and services. To ask for assistance with one of our products please contact our Technical Help staff.

Warning This product is not for human or veterinary use.

Item total €0.00
Shopping cart total €0.00
Size Price Quantity
100 mg €117.00
500 mg €525.00
1 g €932.00
5 g €4,074.00
Pricing updated 2013-05-22.
Prices are subject to change without notice.