10006315  Estradiol

17β-Oestradiol; 17β-Estradiol; β-Estradiol (CAS 50-28-2)




For active pharmaceutical ingredients (APIs) related to Estradiol, see Cayman Pharma

Estrogens direct the development of the female genotype in embryogenesis and at puberty. Estradiol is the major estrogen secreted by the premenopausal ovary. It is synthesized from testosterone primarily in the ovarian granulosa cells and placenta, but small amounts can be produced in the adrenal gland.1,2 Plasma estradiol levels increase gradually between days 1-7 of the menstrual cycle followed by a sharp increase to a peak value of about 300 pg/ml on day 12, just prior to ovulation.3,4
1  Vance, D.E. Cholesterol and related derivatives. 2nd ed., 725-748 (1988).
2  Miller, W.L., Tyrrell, J.B. The adrenal cortex. 3rd edition, 555-711 (1995).
3  Erickson, G.F. The ovary: Basic principles and concepts. A. Physiology. 3rd ed., 973-1015 (1995).
4  Munro, C.J., Stabenfeldt, G.H., Cragun, J.R., et al. Relationship of serum estradiol and progesterone concentrations to the excretion profiles of their major urinary metabolites as measured by enzyme immunoassay and radioimmunoassay. Clin Chem 37 838-844 (1991).

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Pricing Information

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Size Price Quantity
500 mg €10.00
1 g €18.00
5 g €77.00
10 g €135.00
Pricing updated 2010-09-07.
Prices are subject to change without notice.